Pyridines and derivatives

Aromatic organic compounds consist of an aromatic six-membered ring containing one nitrogen atom and five carbon atoms; includes compounds derived from pyridines.

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6,316 – 6,330 of 178,220 results

6,316

Ethos Biosciences Formalin 20% Non-Buffered, 1gal, Ethos

ready-to-use aqueous solution of formaldehyde designed for the fixation and preservation of biological tissues. Unlike buffered formulations, this solution does not contain pH-stabilizing agents, providing a straightforward option for applications where buffering is not required. It is commonly used in histology, pathology, and research laboratories to maintain tissue morphology and enable reliable microscopic evaluation. Prepared under controlled conditions to ensure consistent concentration and quality, 20% Non-Buffered Formalin supports routine and special tissue fixation procedures while streamlining laboratory workflow and reducing preparation time

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6,317

Medchemexpress LLC Recombinant human gp130/IL6ST protein | >95.0% | 50UG

Recombinant human gp130/IL6ST extracellular domain expressed in HEK293 cells and supplied as a lyophilized powder. The protein carries a C-terminal His tag and is formulated from PBS, pH 7.4, with 8% trehalose to support stability for biochemical and cell-based studies.

Recombinant extracellular domain (E23-I618) with C-terminal 8xHis tag.
Purity greater than 95% as determined by reducing SDS-PAGE.
Predicted molecular weight 78-110 kDa for the glycosylated protein.
Lyophilized from PBS, pH 7.4, with 8% trehalose for enhanced stability.
Store at -20°C; reconstituted material stable at 4°C for 1 week or -20°C for longer.
Produced in HEK293 mammalian cells to preserve native glycosylation.

Pricing & Availability

6,318

Medchemexpress LLC Lp-PLA2-IN-1 | 1420367-28-7 | 99.2% | 468.38 | 10 MM * 1 ML

Lp-PLA2-IN-1 is a potent Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. It has potential for atherosclerosis and Alzheimer's disease research. Lp-PLA2 is an enzyme involved in the hydrolysis of lipoprotein lipids or phospholipids. It travels with low-density lipoprotein (LDL) and rapidly cleaves oxidized phosphatidylcholine molecules derived from the oxidation of LDL.

Potent Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor.
Potential for atherosclerosis research.
Potential for Alzheimer's disease research.
Involved in hydrolysis of lipoprotein lipids or phospholipids.
Travels with low-density lipoprotein (LDL).
Cleaves oxidized phosphatidylcholine molecules.

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6,319

BIOHIPPO AAV-hSyn-5HT2m

Recombinant adeno associated virus expressing 5HT2m under the hSyn promoter. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.

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6,320

Medchemexpress LLC Gracillin | 19083-00-2 | 885.04 | 5 MG

Gracillin is a steroidal saponin extracted from plant roots with anti-tumor properties. It can induce apoptosis and autophagy in cancer cells.

Steroidal saponin
Anti-tumor properties
Induces cancer cell apoptosis and autophagy
Shows broad-spectrum inhibitory effects on cancer cell viability
Disrupts mitochondrial function, inhibits ATP production, activates AMPK, and inhibits oxygen consumption rate
Induces ROS generation
Blocks cell cycle in G1 phase and induces apoptosis and autophagy
Inhibits tumor growth in xenograft models and patient-derived xenograft tumors

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6,321

Medchemexpress LLC NITD-349 | 1473450-62-2 | 99.7% | 306.35 | 100 MG

NITD-349 is an MmpL3 inhibitor that shows highly potent anti-mycobacterial activity with MIC50 of 23 nM against virulent Mycobacterium tuberculosis H37Rv. It is for research use only.

Exhibits bactericidal activity against in vitro replicating Mycobacterium tuberculosis (Mtb)
Active against intramacrophage Mtb
Shows high permeability and moderate in vitro metabolic clearance in mouse and human hepatic microsomes
Demonstrated favorable oral pharmacokinetic (PK) properties in rodents and dogs
Efficacious in mouse models of both acute and chronic Mycobacterium tuberculosis infection

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6,322

Apexbio Technology LLC CEP-33779 1257704-57-6 50mg

CEP-33779 (CAS 1257704-57-6) is a highly selective orally active small-molecule inhibitor targeting Janus kinase 2 (JAK2) It demonstrates significant selectivity over other JAK family members with more than 40-fold selectivity over JAK1 and over 800-fold versus TYK2 In cellular assays such as the GeneBLAzer reporter system CEP-33779 effectively inhibits JAK2-mediated signaling in irf-bla TF-1 cells Preclinical studies indicate that CEP-33779 modulates immune responses associated with systemic lupus erythematosus and offers therapeutic benefit in animal models of lupus nephritis and rheumatoid arthritis Additionally it suppresses colorectal tumor growth by inhibiting IL-6/JAK2/STAT3 signaling supporting its utility in inflammation-driven cancer research

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6,323

Medchemexpress LLC Neuropilin-1 antibody (YA3507) | 100 UL

The Neuropilin-1 antibody (YA3507) is a mouse-derived IgG1 monoclonal antibody targeting human Neuropilin-1. This antibody is affinity purified and has an observed molecular weight of 100 kDa. It plays a significant role in binding to VEGF-165, potentially inhibiting its binding to cells and inducing apoptosis. It may also interact with various members of the semaphorin family.

Mouse-derived IgG1 monoclonal antibody
Targets human Neuropilin-1
Affinity purified
Observed molecular weight of 100 kDa
Reacts with human samples
Suitable for WB, FC, and ELISA applications
Stored at -20°C for 1 year, avoiding repeated freeze/thaw cycles

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6,324

Medchemexpress LLC Venanprubart 1mg | 1mg

Venanprubart is an anti-BTLA human IgG4 monoclonal antibody[1] Recommend Isotype Controls Human IgG4 (S228P) kappa Isotype Control (HY-P99003)

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6,325

eMolecules 224311-51-7 | JohnPhos | Medchem Express | MFCD01862440 | 298.410 | C20H27P | 98.000 | CC(C)(C)P(c1ccccc1-c1ccccc1)C(C)(C)C | 5g | 801133625

JohnPhos | Medchem Express | 224311-51-7 | MFCD01862440 | 298.410 | C20H27P | 98.000 | CC(C)(C)P(c1ccccc1-c1ccccc1)C(C)(C)C | 5g | 801133625

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6,326

Apexbio Technology LLC Efavirenz 154598-52-4 50mg

Efavirenz is a non-nucleoside reverse transcriptase inhibitor targeting human immunodeficiency virus type-1 (HIV-1) reverse transcriptase (RT) It functions by binding specifically to an allosteric site of HIV-1 RT thereby inhibiting viral RNA-dependent DNA polymerase activity essential for HIV replication Efavirenz exhibits inhibitory activity against wild-type HIV-1 RT with reported IC95 values ranging from approximately 1 5 to 3 nM and retains inhibitory potency against several known NNRTI-resistant RT variants Due to its molecular mechanism and specificity Efavirenz is frequently utilized in antiviral studies particularly HIV research investigating RT inhibition and HIV resistance mechanisms

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6,327

Apexbio Technology LLC GDC-0152 873652-48-3 50mg

GDC-0152 (CAS 873652-48-3) is a small-molecule antagonist of inhibitor of apoptosis proteins (IAPs) including ML-IAP XIAP cIAP1 and cIAP2 It binds to the BIR domain of ML-IAP and the BIR3 domains of XIAP cIAP1 and cIAP2 with reported Ki values of 14 nM 28 nM 17 nM and 43 nM respectively GDC-0152 promotes degradation of cIAP1 and induces caspase-3/7 activation resulting in reduced viability of breast cancer cells while sparing normal epithelial cells In cellular models GDC-0152 disrupts interactions between XIAP and caspase-9 and between IAPs and Smac supporting its utility in apoptosis-related cancer research

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6,328

Medchemexpress LLC Thy1 (CD90) recombinant protein, mouse, His tag | >95.0% | 500 UG

Recombinant mouse Thy1 (CD90) protein expressed in HEK293 cells with a C-terminal His tag. The protein corresponds to residues Q20-C131 (UniProt P01831) and is purified to ≥95% by reducing SDS-PAGE. Supplied in multiple sizes including a 500 μg vial. For research use only.

Mammalian expression preserves native glycosylation.
C-terminal His tag enables affinity purification and detection.
High purity (≥95%) suitable for biochemical and binding assays.
Corresponds to residues Q20-C131 of the mouse sequence (UniProt P01831).
Supplied in multiple sizes to support different experimental scales.

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6,329

Medchemexpress LLC 1-Methyladenosine | 15763-06-1 | 98.0% | 281.27 | 100 MG

1-Methyladenosine | 15763-06-1 | 98.0% | 281.27 | 100 MG

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6,330

Medchemexpress LLC NS3623 | 343630-41-1 | 99.0% | 427.18 | 100 MG

NS3623 is an activator of human ether-a-go-go-related gene (hERG1/KV11.1) potassium channels. It activates the IKr and Ito currents and exhibits antiarrhythmic effects. It also has a dual mode of action, acting as an inhibitor of hERG1 channels. NS3623 is suitable for laboratory research and studies related to cardiac electrophysiology.

Increases IKr tail currents in isolated canine cardiomyocytes
Shortens corrected QT interval in anesthetized guinea pigs
Improves repolarization reserve
Normalizes ventricular action potentials
Exhibits antiarrhythmic effects

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Pyridines and derivatives

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Medchemexpress LLC Recombinant human gp130/IL6ST protein | >95.0% | 50UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Lp-PLA2-IN-1 | 1420367-28-7 | 99.2% | 468.38 | 10 MM * 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

BIOHIPPO AAV-hSyn-5HT2m Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Gracillin | 19083-00-2 | 885.04 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC NITD-349 | 1473450-62-2 | 99.7% | 306.35 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC CEP-33779 1257704-57-6 50mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Neuropilin-1 antibody (YA3507) | 100 UL Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Venanprubart 1mg | 1mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Efavirenz 154598-52-4 50mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC GDC-0152 873652-48-3 50mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Thy1 (CD90) recombinant protein, mouse, His tag | >95.0% | 500 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1-Methyladenosine | 15763-06-1 | 98.0% | 281.27 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC NS3623 | 343630-41-1 | 99.0% | 427.18 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More